Coronal C-11 Acetate PET Images
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C-11 acetate showed marked uptake in prostate cancer and PET with this tracer is more sensitive in detection of prostate cancer than is FDG-PET. Preoperative staging of pelvic lymph nodes by conventional imaging techniques in prostate cancer is difficult. Studies have shown that C-11 choline PET is sensitive and accurate in preoperative staging of pelvic lymph nodes in prostate cancer and in evaluation of patients with rising PSA after radical prostatectomy or radiation therapy. Patients with rising prostate-specific antigen (PSA) levels after definitive local therapy of prostate carcinoma present a diagnostic dilemma. A local recurrence would be amenable to additional local therapy with curative intent, whereas metastatic disease would require palliative androgen ablation therapy. Preliminary data show that C-11 acetate also is a promising tracer for detection, staging and restaging of prostate cancer.
Oyama N, Akino H, Kanamaru H, et al. 11C-Acetate PET Imaging of Prostate Cancer. J Nucl Med 2002; 43:181-186.
de Jong IJ, Pruim J, Elsinga PH, et al. Preoperative Staging of Pelvic Lymph Nodes in Prostate Cancer by 11C-Choline PET. J Nucl Med 2003; 44:331-335.
Oyama N, Miller TR, Dehdashti F, et al. 11C-Acetate PET Imaging of Prostate Cancer: Detection of Recurrent Disease at PSA Relapse. J Nucl Med 2003; 44:549-555.
Nuńez R, Macapinlac HA, Yeung HWD, et al. Combined 18F-FDG and 11C-Methionine PET Scans in Patients with Newly Progressive Metastatic Prostate Cancer. J Nucl Med 2002; 43:46-55.
References and General Discussion of PET Tumor Imaging Studies (Anatomic field:Genitourinary System, Category:Neoplasm, Neoplastic-like condition)
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