Case Author(s): Yungao Ding, MD, PhD and Henry Royal, MD , 5/14/2001 . Rating: #D., #Q.
Man with refractory complex partial seizure
Coronal brain emission image
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Transaxial brain emission image
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Coronal MRI of the brain
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Transaxial MRI of the brain
Full history/Diagnosis is available below
26 year old man with left frontoparietal open-lip schizencephaly with overlying polymicrogyria presents with refractory complex partial seizures. Clinical evaluation suggests seizures most likely arising from the left frontal region.
9.0 mCi F-18 FDG, i.v.
A defect in the left frontoparietal cortex is noted corresponding to the open-lip schizencephaly on MRI. The left hemisphere is smaller than that of the right and there is enlargement of the left lateral ventricle as showed on MRI.
Schizencephaly, open- or close-lip, is associated with polymicrogyria/agyria in the adjacent cortex. Patients present with seizure, developmental delay, mental retardation and possible blindness if associated with optic nerve hypoplasia.
ACR Codes and Keywords:
References and General Discussion of PET Brain (Nontumor) Imaging Studies (Anatomic field:Skull and Contents, Category:Normal, Technique, Congenital Anomaly)
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Case number: pb011
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