|Patient: 58 year old male|
|History: 57-year-old man with lymphoma.|
|Findings: PET/CT: There is intense FDG uptake in the primary and secondary muscles of respiration, including the intercostal muscles, scalene muscles, sternocleidomastoid muscles, and diaphragm. No increased uptake in the pectoral or abdominal muscles is seen. There is right upper lobe bronchiectasis with surrounding consolidation/"ground glass opacification", demonstrating mild diffuse FDG uptake. Multiple noncalcified parenchymal nodular densities with moderately increased uptake have increased significantly in size since the previous CT. |
Diagnostic CT (one month earlier): There is right upper lobe bronchiectasis with surrounding "ground glass opacity".
|Diagnosis: Increased respiratory muscle exertion due to respiratory distress, likely due to progressive infection or graft versus host disease.|
|General Discussion: This is a 57-year-old man with diffuse large B cell lymphoma treated with allogeneic stem cell transplant approximately 7 months before this study, after having relapsed following multiple regimens of chemotherapy. The patient had been treated for aspergillosis and cytomegalovirus infection previously. A previous bronchial biopsy was negative for graft versus host disease.|
|References: Aydin A, Hickeson M, Yu JQ, Zhuang H, Alavi A. Demonstration of excessive metabolic activity of thoracic and abdominal muscles on FDG-PET in patients with chronic obstructive pulmonary disease. Clin Nucl Med. 2005; 30:159-64.|
Groves A. Extensive skeletal muscle uptake of F18-FDG: relation to immunosuppresants? J Nucl Med Tech 2004; 32:206-8.
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Case Number: 206901Owner(s): Brandon Peters and Barry Siegel, Prof of RadiologyLast Updated: 03-18-2010 The reader is fully responsible for confirming the accuracy of this content.
The reader is fully responsible for confirming the accuracy of this content.