Case Author(s): Scott Winner, M.D. and Keith Fischer, M.D. , 07/26/96 . Rating: #D2, #Q4

Diagnosis: Breast carcinoma

Brief history:

74-year old woman with chest pain.


Projection images from the stress portion of the study.

View main image(mi) in a separate image viewer

View second image(mi). Vertical long axis slices from the cardiac study.

Full history/Diagnosis is available below

Diagnosis: Breast carcinoma

Full history:

74-year old woman with biopsy-proven multifocal right breast cancer. The patient also has had an anterior wall myocardial infarction.


21.5 mCi Tc-99m sestamibi i.v.


There is markedly decreased activity in the anterior wall of the left ventricle. In addition, there is abnormal soft tissue accumulation of tracer in the right axilla.


Technetium-99m-sestamibi uptake can be seen in primary breast cancer and in cancerous lymph nodes.

References: Maublant J, et al. Technetium-99m-Sestamibi Uptake in Breast Tumor and Associated Lymph Nodes. J Nucl Med 1996; 37:922-925



View followup image(mi). Two views of the right breast and axilla.

Major teaching point(s):

Although this is a myocardial imaging study, it is important to examine all extra-cardiac soft tissues for foci of abnormal tracer accumulation.

Differential Diagnosis List

Both benign (uncommonly) disease of the breast and cancer can demonstrate increased uptake with technetium-99m- sestamibi imaging.

ACR Codes and Keywords:

References and General Discussion of Myocardial Imaging (Anatomic field:Breast, Category:Neoplasm, Neoplastic-like condition)

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Case number: mi008

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