Case Author(s): Scott Winner, M.D. and Keith Fischer, M.D. , 07/26/96 . Rating: #D2, #Q4

Diagnosis: Breast carcinoma

Brief history:

74-year old woman with chest pain.

Images:

Projection images from the stress portion of the study.

View main image(mi) in a separate image viewer

View second image(mi). Vertical long axis slices from the cardiac study.

Full history/Diagnosis is available below


Diagnosis: Breast carcinoma

Full history:

74-year old woman with biopsy-proven multifocal right breast cancer. The patient also has had an anterior wall myocardial infarction.

Radiopharmaceutical:

21.5 mCi Tc-99m sestamibi i.v.

Findings:

There is markedly decreased activity in the anterior wall of the left ventricle. In addition, there is abnormal soft tissue accumulation of tracer in the right axilla.

Discussion:

Technetium-99m-sestamibi uptake can be seen in primary breast cancer and in cancerous lymph nodes.

References: Maublant J, et al. Technetium-99m-Sestamibi Uptake in Breast Tumor and Associated Lymph Nodes. J Nucl Med 1996; 37:922-925

Followup:

None

View followup image(mi). Two views of the right breast and axilla.

Major teaching point(s):

Although this is a myocardial imaging study, it is important to examine all extra-cardiac soft tissues for foci of abnormal tracer accumulation.

Differential Diagnosis List

Both benign (uncommonly) disease of the breast and cancer can demonstrate increased uptake with technetium-99m- sestamibi imaging.

ACR Codes and Keywords:

References and General Discussion of Myocardial Imaging (Anatomic field:Breast, Category:Neoplasm, Neoplastic-like condition)

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Case number: mi008

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